Commensal Bifidobacterium promotes antitumor immunity and facilitates anti–PD-L1 efficacy-Reference-Cited by-同舟云学术

Commensal Bifidobacterium promotes antitumor immunity and facilitates anti–PD-L1 efficacy

Published:2015-11-27 Issue:6264 Volume:350 Page:1084-1089
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Sivan Ayelet¹,Corrales Leticia¹,Hubert Nathaniel²,Williams Jason B.¹,Aquino-Michaels Keston³,Earley Zachary M.²,Benyamin Franco W.¹,Man Lei Yuk²,Jabri Bana²,Alegre Maria-Luisa²,Chang Eugene B.²,Gajewski Thomas F.¹²

Affiliation:

1. Department of Pathology, University of Chicago, Chicago, IL 60637, USA.

2. Department of Medicine, University of Chicago, Chicago, IL 60637, USA.

3. Section of Genetic Medicine, University of Chicago, Chicago, IL 60637, USA.

Funder

NIH

National Institute of Diabetes and Digestive and Kidney Diseases

Cancer Research Institute

Melanoma Research Alliance

P30 Digestive Disease Research Core Center

University of Chicago Cancer Biology

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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3. PD-1 blockade induces responses by inhibiting adaptive immune resistance

4. Up-Regulation of PD-L1, IDO, and T regs in the Melanoma Tumor Microenvironment Is Driven by CD8 + T Cells

5. An immune-active tumor microenvironment favors clinical response to ipilimumab

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