Up-Regulation of PD-L1, IDO, and T regs in the Melanoma Tumor Microenvironment Is Driven by CD8 + T Cells-Reference-Cited by-同舟云学术

Up-Regulation of PD-L1, IDO, and T regs in the Melanoma Tumor Microenvironment Is Driven by CD8 + T Cells

Author:

Spranger Stefani¹,Spaapen Robbert M.¹,Zha Yuanyuan²,Williams Jason¹,Meng Yuru¹,Ha Thanh T.¹,Gajewski Thomas F.¹²

Affiliation:

1. Department of Pathology, Section of Hematology/Oncology, University of Chicago, Chicago, IL 60637, USA.

2. Department of Medicine, Section of Hematology/Oncology, University of Chicago, Chicago, IL 60637, USA.

Abstract

CD8 + T cells induce immunosuppressive mechanisms in the tumor microenvironment.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference49 articles.

1. High-dose recombinant interleukin-2 therapy in patients with metastatic melanoma: Long-term survival update.;Atkins M. B.;Cancer J. Sci. Am.,2000

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