Border Control—A Membrane-Linked Interactome of Arabidopsis

Author:

Jones Alexander M.1,Xuan Yuanhu1,Xu Meng1,Wang Rui-Sheng2,Ho Cheng-Hsun1,Lalonde Sylvie1,You Chang Hun1,Sardi Maria I.1,Parsa Saman A.1,Smith-Valle Erika1,Su Tianying1,Frazer Keith A.1,Pilot Guillaume13,Pratelli Réjane13,Grossmann Guido1,Acharya Biswa R.4,Hu Heng-Cheng5,Engineer Cawas6,Villiers Florent5,Ju Chuanli5,Takeda Kouji5,Su Zhao4,Dong Qunfeng7,Assmann Sarah M.4,Chen Jin18,Kwak June M.59,Schroeder Julian I.6,Albert Reka2,Rhee Seung Y.1,Frommer Wolf B.1

Affiliation:

1. Department of Plant Biology, Carnegie Institution for Science, CA 94305, USA.

2. Department of Physics, Pennsylvania State University, University Park, PA 16802, USA.

3. Department of Plant Pathology, Physiology, and Weed Science, Virginia Polytechnic University and State University, Blacksburg, VA 24061, USA.

4. Department of Biology, Pennsylvania State University, University Park, PA 16802, USA.

5. Department of Cell Biology and Molecular Genetics, University of Maryland, College Park, MD 20742, USA.

6. Cell and Developmental Biology Section, Division of Biological Sciences, University of California, San Diego, La Jolla, CA 92093, USA.

7. Department of Biological Sciences, University of North Texas, Denton, TX 76203, USA.

8. Michigan State University–U.S. Department of Energy (MSU-DOE) Plant Research Laboratory and Department of Computer Science and Engineering, Michigan State University, East Lansing, MI 48824, USA.

9. Center for Plant Aging Research, Institute for Basic Science, Department of New Biology, Daegu Gyeongbuk Institute of Science and Technology, Daegu 711-873, Republic of Korea.

Abstract

Degrees of Separation Proteins embedded in membranes represent an interesting point of communication between the cell and its environment, but their localization to membranes can make them difficult to study. Jones et al. (p. 711 ) found an approach to catalog thousands of interactions involving membrane proteins and membrane-associated signaling machinery—including many previously uncharacterized proteins. With a focus on the model plant Arabidopsis , several of the identified interactions fill gaps in important signal transduction chains, while others point to functions for enigmatic unknown proteins.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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