Unearthing Neanderthal population history using nuclear and mitochondrial DNA from cave sediments-Reference-Cited by-同舟云学术

Unearthing Neanderthal population history using nuclear and mitochondrial DNA from cave sediments

Published:2021-05-07 Issue:6542 Volume:372 Page:
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Vernot Benjamin¹^ORCID,Zavala Elena I.¹^ORCID,Gómez-Olivencia Asier²³⁴^ORCID,Jacobs Zenobia⁵⁶^ORCID,Slon Viviane¹⁷⁸^ORCID,Mafessoni Fabrizio¹^ORCID,Romagné Frédéric¹,Pearson Alice¹,Petr Martin¹^ORCID,Sala Nohemi⁴⁹^ORCID,Pablos Adrián⁴⁹^ORCID,Aranburu Arantza²³,de Castro José María Bermúdez⁹,Carbonell Eudald¹⁰¹¹,Li Bo⁵⁶^ORCID,Krajcarz Maciej T.¹²^ORCID,Krivoshapkin Andrey I.¹³¹⁴^ORCID,Kolobova Kseniya A.¹³^ORCID,Kozlikin Maxim B.¹³^ORCID,Shunkov Michael V.¹³^ORCID,Derevianko Anatoly P.¹³^ORCID,Viola Bence¹⁵^ORCID,Grote Steffi¹,Essel Elena¹,Herráez David López¹,Nagel Sarah¹,Nickel Birgit¹,Richter Julia¹,Schmidt Anna¹,Peter Benjamin¹^ORCID,Kelso Janet¹^ORCID,Roberts Richard G.⁵⁶^ORCID,Arsuaga Juan-Luis⁴¹⁶^ORCID,Meyer Matthias¹^ORCID

Affiliation:

1. Department of Evolutionary Genetics, Max-Planck-Institute for Evolutionary Anthropology, Leipzig, Germany.

2. Departamento de Geología, Facultad de Ciencia y Tecnología, Universidad del País Vasco-Euskal Herriko Unibertsitatea (UPV/EHU), Leioa, Spain.

3. Sociedad de Ciencias Aranzadi, Donostia-San Sebastián, Spain.

4. Centro Mixto UCM-ISCIII de Evolución y Comportamiento Humanos, Madrid, Spain.

5. Centre for Archaeological Science, School of Earth, Atmospheric and Life Sciences, University of Wollongong, Wollongong, New South Wales, Australia.

6. Australian Research Council (ARC) Centre of Excellence for Australian Biodiversity and Heritage, University of Wollongong, Wollongong, New South Wales, Australia.

7. Department of Anatomy and Anthropology and Department of Human Molecular Genetics and Biochemistry, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

8. The Dan David Center for Human Evolution and Biohistory Research, Tel Aviv University, 6997801 Tel Aviv, Israel.

9. Centro Nacional de Investigación Sobre la Evolución Humana (CENIEH), Burgos, Spain.

10. Institut Català de Paleoecologia Humana i Evolució Social (IPHES), Universitat Rovira i Virgili, Tarragona, Spain.

11. Àrea de Prehistòria, Universitat Rovira i Virgili, Tarragona, Spain.

12. Institute of Geological Sciences, Polish Academy of Sciences, Warszawa, Poland.

13. Institute of Archaeology and Ethnography, Russian Academy of Sciences, Novosibirsk, Russia.

14. Novosibirsk State University, Novosibirsk, Russia.

15. Department of Anthropology, University of Toronto, Toronto, Ontario, Canada.

16. Departamento de Paleontología, Facultad Ciencias Geológicas, Universidad Complutense de Madrid, Madrid, Spain.

Abstract

The value of dirty DNA Environmental DNA can identify the presence of species, even from the distant past. Surveying three cave sites in western Europe and southern Siberia, Vernot et al. identified nuclear DNA and confirmed that it is from the close relatives of anatomically modern humans—Neanderthal and Denisovan individuals. A phylogenetic analysis and modeling show that the DNA in sediment samples from several layers corresponds to previously studied skeletal remains. These results demonstrate that environmental data can be applied to study the population genetics of the extinct Neanderthal and Denisovan lineages, identifying a turnover of Neanderthal populations ∼100,000 years ago. Science , this issue p. eabf1667

Funder

H2020 European Research Council

Social Sciences and Humanities Research Council of Canada

European Research Council

Australian Research Council

Russian Foundation for Basic Research

Russian Science Foundation

European Regional Development Fund

Agencia Estatal de Investigación

Max Planck Society

Junta de Castilla y León and Fundación Atapuerca

National Science Center, Poland