Affiliation:
1. Bioinformatics Research Group, SRI International, EK223, 333 Ravenswood Avenue, Menlo Park, CA 94025, USA.
Abstract
A pathway database (DB) is a DB that describes biochemical pathways, reactions, and enzymes. The EcoCyc pathway DB (see
http://ecocyc.org
) describes the metabolic, transport, and genetic-regulatory networks of
Escherichia coli
. EcoCyc is an example of a computational symbolic theory, which is a DB that structures a scientific theory within a formal ontology so that it is available for computational analysis. It is argued that by encoding scientific theories in symbolic form, we open new realms of analysis and understanding for theories that would otherwise be too large and complex for scientists to reason with effectively.
Publisher
American Association for the Advancement of Science (AAAS)
Cited by
172 articles.
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