Natural Iron Isotope Variations in Human Blood-Reference-Cited by-同舟云学术

Natural Iron Isotope Variations in Human Blood

Published:2002-03-15 Issue:5562 Volume:295 Page:2065-2066
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Walczyk Thomas¹,von Blanckenburg Friedhelm²

Affiliation:

1. Laboratory of Human Nutrition, Institute of Food Sciences, Swiss Federal Institute of Technology (ETH) Zurich, Seestrasse 72, CH-8803 Rüschlikon, Switzerland.

2. Isotope Geology, University of Berne, Erlachstrasse 9a, CH-3012 Berne, Switzerland.

Abstract

Isotopic analysis of human blood and liver and muscle tissue indicates that each individual bears a long-term iron (Fe) isotope signature in the blood. Blood and tissue differ slightly in isotopic composition and are depleted by up to 2.6 per mil in 56 Fe relative to 54 Fe when compared to dietary Fe. The 56 Fe/ 54 Fe isotope ratio in the blood of males is, on average, lower by 0.3 per mil than that of females. These results suggest that Fe isotope effects in the blood reflect differences in intestinal Fe absorption between individuals and genotypes.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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5. Iron Isotope Biosignatures

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