A Conformation of Cyclosporin A in Aqueous Environment Revealed by the X-Ray Structure of a Cyclosporin-Fab Complex-Reference-Cited by-同舟云学术

A Conformation of Cyclosporin A in Aqueous Environment Revealed by the X-Ray Structure of a Cyclosporin-Fab Complex

Published:1992-04-03 Issue:5053 Volume:256 Page:92-94
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Altschuh Danièle¹,Vix Olivier²,Rees Bernard²,Thierry Jean-Claude²

Affiliation:

1. Laboratoire d'immunochimie, Institut de Biologie Moléculaire et Cellulaire du CNRS,67084 Strasbourg, France.

2. Laboratoire de Cristallographie, Institut de Biologie Moléculaire et Cellulaire du CNRS, 67084 Strasbourg, France.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference35 articles.

1. ALTSCHUH, D, CRYSTALLIZATION AND PRELIMINARY-X-RAY INVESTIGATION OF A COMPLEX BETWEEN A FAB FRAGMENT AND ITS ANTIGEN, CYCLOSPORINE, JOURNAL OF MOLECULAR BIOLOGY 209: 177 (1989).

2. BOREL, J.F., COMPARATIVE-STUDY OF INVITRO AND INVIVO DRUG EFFECTS ON CELL-MEDIATED CYTOTOXICITY, IMMUNOLOGY 31: 631 (1976).

3. X-PLOR Manual Version 2.1 1990

4. Crowther, R. A., The Molecular Replacement Method: 173 (1972).

5. CYGLER, M, APPLICATION OF THE MOLECULAR REPLACEMENT METHOD TO MULTIDOMAIN PROTEINS .1. DETERMINATION OF THE ORIENTATION OF AN IMMUNOGLOBULIN FAB FRAGMENT, ACTA CRYSTALLOGRAPHICA SECTION A 44: 38 (1988).

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