A transcription factor hierarchy defines an environmental stress response network

Author:

Song Liang1,Huang Shao-shan Carol1,Wise Aaron2,Castanon Rosa3,Nery Joseph R.3,Chen Huaming3,Watanabe Marina1,Thomas Jerushah1,Bar-Joseph Ziv2,Ecker Joseph R.134

Affiliation:

1. Plant Biology Laboratory, Salk Institute for Biological Studies, La Jolla, CA 92037, USA.

2. Computational Biology Department, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA 15213, USA.

3. Genomic Analysis Laboratory, Salk Institute for Biological Studies, La Jolla, CA 92037, USA.

4. Howard Hughes Medical Institute (HHMI), Salk Institute for Biological Studies, La Jolla, CA 92037, USA.

Abstract

Complex transcription factor interactions To respond to environmental changes, such as drought, plants must regulate numerous cellular processes. Working in the model plant Arabidopsis , Song et al. profiled the binding of 21 transcription factors to chromatin and mapped the complex gene regulatory networks involved in the response to the plant hormone abscisic acid. The work provides a framework for understanding and modulating plant responses to stress. Science , this issue p. 598

Funder

Gordon and Betty Moore Foundation

NSF

NIH

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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