Moving CTLA-4 from the trash to recycling
Author:
Affiliation:
1. Institute of Immunity and Transplantation, University College London, Royal Free Hospital, London, UK.
Abstract
Publisher
American Association for the Advancement of Science (AAAS)
Subject
Multidisciplinary
Reference15 articles.
1. The future of immune checkpoint therapy
2. The emerging role of CTLA4 as a cell-extrinsic regulator of T cell responses
3. Patients with LRBA deficiency show CTLA4 loss and immune dysregulation responsive to abatacept therapy
4. The self-obsession of T cells: how TCR signaling thresholds affect fate 'decisions' and effector function
5. Intrinsic and extrinsic control of peripheral T-cell tolerance by costimulatory molecules of the CD28/ B7 family
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1. CTLA-4 expression on CD4+ lymphocytes in patients with sepsis-associated immunosuppression and its relationship to mTOR mediated autophagic–lysosomal disorder;Frontiers in Immunology;2024-07-22
2. mTOR Deletion Alleviates CD4+ T‐Cell Dysfunction in Sepsis through Reducing CTLA4 Accumulation Mediated by Rescuing Autophagy;Mediators of Inflammation;2024-01
3. Functional Relevance of CTLA4 Variants: an Upgraded Approach to Assess CTLA4-Dependent Transendocytosis by Flow Cytometry;Journal of Clinical Immunology;2023-09-23
4. CTLA-4 tail fusion enhances CAR-T antitumor immunity;Nature Immunology;2023-07-27
5. CTLA-4 tail fusion enhances CAR-T anti-tumor immunity;2023-03-15
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