Global epistasis makes adaptation predictable despite sequence-level stochasticity-Reference-Cited by-同舟云学术

Global epistasis makes adaptation predictable despite sequence-level stochasticity

Published:2014-06-27 Issue:6191 Volume:344 Page:1519-1522
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Kryazhimskiy Sergey¹²,Rice Daniel P.¹²,Jerison Elizabeth R.³²,Desai Michael M.¹³²

Affiliation:

1. Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA 02138, USA.

2. FAS Center for Systems Biology, Harvard University, Cambridge, MA 02138, USA.

3. Department of Physics, Harvard University, Cambridge, MA 02138, USA.

Abstract

Clouding evolution's crystal ball Because of a sort of mutation buffering process, different starting mutations can tend to end up with similar overall affects on an organism's fitness. Kryazhimskiy et al. evolved lines of yeast, each originating from distinct single genotypes, under the same selective regimen. A subset of clones from these adapted populations was subjected to fitness assays and sequenced. Populations with lower initial fitness, adapted more rapidly than populations with higher initial fitness, so that in the end the fitness levels were similar. Science , this issue p. 1519

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference29 articles.

1. Second-Order Selection for Evolvability in a Large Escherichia coli Population

2. Historical contingency and the evolution of a key innovation in an experimental population of Escherichia coli

3. Permissive Secondary Mutations Enable the Evolution of Influenza Oseltamivir Resistance

4. Epistasis between Beneficial Mutations and the Phenotype-to-Fitness Map for a ssDNA Virus

5. Evolvability of an RNA virus is determined by its mutational neighbourhood

Cited by 381 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Candida albicans’inorganic phosphate transport and evolutionary adaptation to phosphate scarcity;2024-01-30

2. Adaptive and pleiotropic effects of evolution in synonymous sugar environments;2024-01-30

3. Adaptation to complex environments reveals pervasive trade-offs and genomic targets with large pleiotropic effects;2024-01-25

4. A dynamical limit to evolutionary adaptation;Proceedings of the National Academy of Sciences;2024-01-19

5. Quantifying the strength of viral fitness tradeoffs between hosts: A meta-analysis of pleiotropic fitness effects;2023-12-16