Mitochondrial Replacement, Evolution, and the Clinic-Reference-Cited by-同舟云学术

Mitochondrial Replacement, Evolution, and the Clinic

Published:2013-09-20 Issue:6152 Volume:341 Page:1345-1346
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Reinhardt Klaus¹²,Dowling Damian K.³,Morrow Edward H.⁴

Affiliation:

1. Animal Evolutionary Ecology, University of Tuebingen, 72076 Tuebingen, Germany.

2. Department of Animal and Plant Sciences, University of Sheffield, Sheffield S10 2TN, UK.

3. School of Biological Sciences, Monash University, 3800 Victoria, Australia.

4. Evolution, Behaviour, and Environment Group, School of Life Sciences, University of Sussex Brighton BN1 9QG, UK.

Abstract

Mitochondrial replacement therapy might bear health risks, especially for males.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference15 articles.

1. Mitochondrial DNA mutations in human disease

2. Sato A., et al.., Proc. Natl. Acad. Sci. U.S.A. 102, 16765–16770 (2005).

3. Mitochondrial gene replacement in primate offspring and embryonic stem cells

4. Pronuclear transfer in human embryos to prevent transmission of mitochondrial DNA disease

5. Haites N. Lovell-Badge R. “Scientific review of the safety and efficacy of methods to avoid mitochondrial disease through assisted conception” (HFEA London 2011); www.hfea.gov.uk/docs/2011-04-18_Mitochondria_review_-_final_report.PDF.

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