Countering imprecision in precision medicine

Author:

Hey Spencer Phillips1,Kesselheim Aaron S.1

Affiliation:

1. Program On Regulation, Therapeutics, and Law (PORTAL), Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02120, USA, and Center for Bioethics, Harvard Medical School, Boston, MA 02115, USA.

Abstract

Better coordination is needed to study complex interventions

Funder

Genome Canada

Genome Quebec

Genome Alberta

Canadian Institutes for Health Research (CIHR)

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference13 articles.

1. National Academies of Sciences, Engineering, and Medicine, Biomarker Tests For Molecularly Targeted Therapies: Key to Unlocking Precision Medicine (National Academies Press, Washington, DC, 2016).

2. Breaking a Vicious Cycle

3. Pragmatic issues in biomarker evaluation for targeted therapies in cancer

4. How Do You Tell Whether a Breast Cancer is HER2 Positive? Ongoing Studies Keep Debate in High Gear

5. Office of Public Health Strategy and Analysis, FDA, The Public Health Evidence for FDA Oversight of Laboratory Developed Tests: 20 Case Studies (FDA, Silver Spring, MD, 2015).

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