1. Howard Hughes Medical Institute, University of Iowa, Iowa City, IA 52242, USA.
2. Department of Physiology and Biophysics, University of Iowa, Iowa City, IA 52242, USA.
3. Department of Neurology, University of Iowa, Iowa City, IA 52242, USA.
4. Department of Internal Medicine, University of Iowa, Iowa City, IA 52242, USA.
5. Department of Pharmacology, University of Iowa, Iowa City, IA 52242, USA.