Barcoded microbial system for high-resolution object provenance-Reference-Cited by-同舟云学术

Barcoded microbial system for high-resolution object provenance

Published:2020-06-05 Issue:6495 Volume:368 Page:1135-1140
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Qian Jason¹²³^ORCID,Lu Zhi-xiang¹²^ORCID,Mancuso Christopher P.⁴^ORCID,Jhuang Han-Ying¹^ORCID,del Carmen Barajas-Ornelas Rocío⁵^ORCID,Boswell Sarah A.¹²^ORCID,Ramírez-Guadiana Fernando H.⁵^ORCID,Jones Victoria¹⁶,Sonti Akhila⁴,Sedlack Kole⁴^ORCID,Artzi Lior⁵^ORCID,Jung Giyoung⁷^ORCID,Arammash Mohammad¹^ORCID,Pettit Mary E.¹^ORCID,Melfi Michael¹,Lyon Lorena¹,Owen Siân V.⁶^ORCID,Baym Michael²⁶^ORCID,Khalil Ahmad S.⁴⁸^ORCID,Silver Pamela A.¹⁸^ORCID,Rudner David Z.⁵,Springer Michael¹²^ORCID

Affiliation:

1. Department of Systems Biology, Harvard Medical School, Boston, MA 02115, USA.

2. Laboratory of Systems Pharmacology, Harvard Medical School, Boston, MA 02115, USA.

3. Biological and Biomedical Sciences Program, Harvard Medical School, Boston, MA 02115, USA.

4. Department of Biomedical Engineering and Biological Design Center, Boston University, Boston, MA 02215, USA.

5. Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02115, USA.

6. Department of Biomedical Informatics, Harvard Medical School, Boston, MA 02115, USA.

7. Synthetic Biology Center, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

8. Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115, USA.

Abstract

DNA barcodes in small packages Under adverse environmental conditions, some microorganisms form spores that provide robust protection for genetic material. Qian et al. developed a system in which DNA barcodes are encapsulated inside nongerminating microbial spores and can be dispersed on objects or in the environment (see the Perspective by Nivala). These barcoded spores provide a durable, specific marker that can be read out quickly with simple equipment. When applied to soil, the spores can be transferred to and from objects around them, enabling tracking at meter-scale resolution. On plant leaves, the spores are not readily transferred, and the authors demonstrate a potential use for tracking agricultural products. Science , this issue p. 1135 ; see also p. 1058

Funder

Defense Advanced Research Projects Agency

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference26 articles.

1. Systems for sustainability and transparency of food supply chains – Current status and challenges

2. Taggant materials in forensic science: A review

3. Longitudinal analysis of microbial interaction between humans and the indoor environment

4. Dynamic Human Environmental Exposome Revealed by Longitudinal Personal Monitoring

5. Forensic analysis of the microbiome of phones and shoes

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