Engineering alcohol tolerance in yeast-Reference-Cited by-同舟云学术

Engineering alcohol tolerance in yeast

Published:2014-10-03 Issue:6205 Volume:346 Page:71-75
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Lam Felix H.¹²,Ghaderi Adel¹,Fink Gerald R.²,Stephanopoulos Gregory¹

Affiliation:

1. Department of Chemical Engineering, Massachusetts Institute of Technology (MIT), Cambridge, MA, USA.

2. Whitehead Institute for Biomedical Research, Cambridge, MA, USA.

Abstract

Tricks for boosting yeast's ethanol yields To become a widely used source of fuel, widespread industrial production of ethanol using yeast needs to be simple and efficient. However, two conditions ideal for boosting production—tolerance of higher temperatures and high concentrations of ethanol—have been limiting (see the Perspective by Cheng and Kao). Now, Caspeta et al. have used adaptive laboratory evolution to find yeast strains that can tolerate high temperatures and Lam et al. have identified a route to improve yeast's resistance to high concentrations of ethanol. Science , this issue p. 75 , p. 71 ; see also p. 35

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference33 articles.

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5. Identification of novel causative genes determining the complex trait of high ethanol tolerance in yeast using pooled-segregant whole-genome sequence analysis

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