Restoring Systemic GDF11 Levels Reverses Age-Related Dysfunction in Mouse Skeletal Muscle-Reference-Cited by-同舟云学术

Restoring Systemic GDF11 Levels Reverses Age-Related Dysfunction in Mouse Skeletal Muscle

Published:2014-05-09 Issue:6184 Volume:344 Page:649-652
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Sinha Manisha¹²³⁴,Jang Young C.¹²⁴,Oh Juhyun¹²⁴,Khong Danika¹²⁴,Wu Elizabeth Y.¹²⁴,Manohar Rohan¹²⁴,Miller Christine¹²⁴,Regalado Samuel G.¹⁵,Loffredo Francesco S.¹⁶,Pancoast James R.¹⁶,Hirshman Michael F.²,Lebowitz Jessica¹²⁴,Shadrach Jennifer L.¹²³,Cerletti Massimiliano¹²,Kim Mi-Jeong²,Serwold Thomas²,Goodyear Laurie J.²⁷,Rosner Bernard⁸,Lee Richard T.¹⁶,Wagers Amy J.¹²³⁴

Affiliation:

1. Harvard Stem Cell Institute and Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA.

2. Joslin Diabetes Center, Boston, MA 02215, USA.

3. Howard Hughes Medical Institute, Cambridge, MA, USA.

4. Paul F. Glenn Laboratories for the Biological Mechanisms of Aging, Harvard Medical School, Boston, MA, USA.

5. University of California, Berkeley, CA, USA.

6. Cardiovascular Division, Department of Medicine, Brigham and Women’s Hospital and the Brigham Regenerative Medicine Center, Boston, MA, USA.

7. Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA, USA.

8. Department of Biostatistics, Harvard School of Public Health, Boston, MA, USA.

Abstract

Help the Aged Muscle function declines with age, as does neurogenesis in certain brain regions. Two teams analyzed the effects of heterochronic parabiosis in mice. Sinha et al. (p. 649 ) found that when an aged mouse shares a circulatory system with a youthful mouse, the aged mouse sees improved muscle function, and Katsimpardi et al. (p. 630 ) observed increased generation of olfactory neurons. In both cases, Growth Differentiation Factor 11 appeared to be one of the key components of the young blood.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference25 articles.

1. SATELLITE CELL OF SKELETAL MUSCLE FIBERS

2. Skeletal Muscle Stem Cells: Effects of Aging and Metabolism on Muscle Regenerative Function

3. Isolation of Adult Mouse Myogenic Progenitors

4. Highly Efficient, Functional Engraftment of Skeletal Muscle Stem Cells in Dystrophic Muscles

5. Short-Term Calorie Restriction Enhances Skeletal Muscle Stem Cell Function

Cited by 683 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. AnnoPRO: a strategy for protein function annotation based on multi-scale protein representation and a hybrid deep learning of dual-path encoding;Genome Biology;2024-02-01

2. MuSCs and IPCs: roles in skeletal muscle homeostasis, aging and injury;Cellular and Molecular Life Sciences;2024-01-30

3. Antiaging Strategies and Remedies: A Landscape of Research Progress and Promise;ACS Chemical Neuroscience;2024-01-12

4. The regulatory effect of growth differentiation factor 11 on different cells;Frontiers in Immunology;2023-12-08

5. Cancer Cachexia: New Insights and Future Directions;Cancers;2023-11-26