Real-Time Observation of Transcription Initiation and Elongation on an Endogenous Yeast Gene-Reference-Cited by-同舟云学术

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Real-Time Observation of Transcription Initiation and Elongation on an Endogenous Yeast Gene

Published:2011-04-22 Issue:6028 Volume:332 Page:475-478
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Larson Daniel R.¹²³,Zenklusen Daniel¹⁴,Wu Bin¹²,Chao Jeffrey A.¹,Singer Robert H.¹²³

Affiliation:

1. Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

2. Gruss-Lipper Biophotonics Center, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

3. Transcription Imaging Consortium, Janelia Farm Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20147, USA.

4. Département de biochimie, Université de Montréal, Montréal, Québec H3T 1J4, Canada.

Abstract

In yeast, the initiation of gene expression is stochastic and is controlled by transcription factor search times.

Funder

National Institute of General Medical Sciences

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Link

http://www.sciencemag.org/content/332/6028/475.full.pdf

Reference27 articles.

1. A canonical promoter organization of the transcription machinery and its regulators in the Saccharomyces genome

2. Transcriptional regulatory code of a eukaryotic genome

3. Transcription Dynamics

4. Imaging Transcription in Living Cells

5. Localization of ASH1 mRNA Particles in Living Yeast

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