Guided Tour to the Heart of RISC-Reference-Cited by-同舟云学术

Guided Tour to the Heart of RISC

Published:2012-05-25 Issue:6084 Volume:336 Page:985-986
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Kaya Emine¹,Doudna Jennifer A.¹²³⁴

Affiliation:

1. Department of Molecular and Cell Biology.

2. Howard Hughes Medical Institute, University of California, Berkeley, CA 94720, USA.

3. Department of Chemistry, University of California, Berkeley, CA 94720, USA.

4. Physical Biosciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA.

Abstract

The crystal structures of human and yeast Argonaute proteins reveal the intricacies of the multidomain enzyme at the hub of the RNA interference machinery.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference11 articles.

1. The Crystal Structure of Human Argonaute2

2. Hsc70/Hsp90 Chaperone Machinery Mediates ATP-Dependent RISC Loading of Small RNA Duplexes

3. Structure of C3PO and mechanism of human RISC activation

4. Crystal Structure of Argonaute and Its Implications for RISC Slicer Activity

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