Membrane Cholesterol, Protein Phosphorylation, and Lipid Rafts-Reference-Cited by-同舟云学术

Membrane Cholesterol, Protein Phosphorylation, and Lipid Rafts

Published:2001-01-30 Issue:67 Volume:2001 Page:
ISSN:1525-8882
Container-title:Science's STKE
language:en
Short-container-title:Sci. STKE

Author:

Edidin Michael¹

Affiliation:

1. The author is in the Department of Biology, Johns Hopkins University, 34th and Charles Streets, Baltimore, MD 21218, USA.

Abstract

The functions of cholesterol and membrane microdomains in transmembrane signaling remain controversial. Edidin discusses the questions surrounding lipid rafts, membrane microdomains that have been biochemically defined but are difficult to visualize in vivo. He also discusses whether experiments showing correlation of changes in plasma membrane cholesterol with differentiation and the formation of adherens junctions in endothelial cells are consistent with a model in which lipid rafts influence the regulation of these processes.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference26 articles.

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2. Structure and Function of Sphingolipid- and Cholesterol-rich Membrane Rafts

3. The role of lipid rafts in T cell antigen receptor (TCR) signalling

4. Cell Confluence-dependent Remodeling of Endothelial Membranes Mediated by Cholesterol

5. Lipid composition and lateral diffusion in plasma membranes of teratocarcinoma-derived cell lines

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