Optimal Control of a Time Delayed HIV-1 Infection Model
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Published:2019-04-29
Issue:2
Volume:12
Page:506-518
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ISSN:1307-5543
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Container-title:European Journal of Pure and Applied Mathematics
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language:
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Short-container-title:Eur. J. Pure Appl. Math.
Author:
Ali Nigar,Chohan Muhammad Ikhlaq,Zaman Gul
Abstract
In this paper, an optimal control problem of HIV infection model of delay differential equations is taken into account. Then we set a control function which represents the efficiency of reverse transcriptase inhibitors. Objective functional is constructed to minimize the virus concentration as well as treatment costs.Adjoint system is derived using Pontryagins Maximum Principle. Optimality system is calculated and numerical simulation is carried out to illustrate the theoretical results. Finally, conclusion is drawn
Publisher
New York Business Global LLC
Subject
Applied Mathematics,Geometry and Topology,Numerical Analysis,Statistics and Probability,Algebra and Number Theory,Theoretical Computer Science
Cited by
1 articles.
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