Phytochemical profile of eleven peruvian Mentheae. Isolation of ursolic acid from Clinopodium revolutum (Ruiz & Pavon) Govaerts and analysis of the aqueous infusions

Author:

Serrano Carlos A.1,Villena Gretty K.2,Rodriguez Eric F.3,Calsino Belea4,Ludeña Michael1,Ccana Gari V.5

Affiliation:

1. Universidad Nacional de San Antonio Abad del Cusco, PERU

2. Universidad Nacional Agraria La Molina, Perú

3. Universidad Nacional de Trujillo, Perú

4. Centro de Salud Minsa, Pisaq Perú

5. Farmacia Magistral Solidaridad, Cusco-Perú

Abstract

Abstract The profile of secondary metabolites in eleven Mentheae (Nepetoideae, Lamiaceae) from Peru by liquid chromatography associated with Orbitrap mass spectrometry, UHPLC-OT-MS is presented. Precursors of and salvianolic acids have been found, particularly rosmarinic acid, as well as a diversity of free and glycosylated flavonoids as main substances, 127 tentatively identified structures. In addition, a method to obtain ursolic acid from Clinopodium revolutum (R. & P.) Govaerts and a quantitative analysis for rosmarinic acid and triterpenic acids in aqueous infusions of these plants are presented.

Publisher

Research Square Platform LLC

Reference62 articles.

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4. Molecular Phylogeny of Menthinae (Lamiaceae, Nepetoideae, Mentheae)-taxonomy, biogeography and conflicts;Bräuchler C;Molecular Phylogenetics & Evolution,2010

5. Biogeography, and staminal evolution in the tribe Mentheae (Lamiaceae);Drew B;American J. Botany,2012

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