Evaluation of dyslipidemia based on ATP ⅠⅠⅠ guideline in adults of southwest Iran: A population-based study

Abstract

Abstract Background Dyslipidemia is a main risk factor for cardiovascular disease. The prevalence of dyslipidemia was 22.6–81% across Africa, South East Asia, Europe, the Americas and Iran. We aimed to investigate the occurrence of dyslipidemia and its associated risk factors in the southwest region of Iran. Methods This population-based cross-sectional study was conducted on 9846 participants aged 35–70 years of the Hoveyzeh Cohort Study in southwest Iran during 2016–2018. Information on socioeconomic factors, demographic characteristics, comorbidities, laboratory tests, anthropometric measurements, and lifestyle was collected. The criteria for dyslipidemia were based on the ATP III classification for adults. The chi-square test was used for analysis. Also, multiple logistic regression was used to control the potential confounders. Results Among 9846 participants, the mean ± SD of age was 48.8 ± 9.2 years, and 59.1% of them were women. The overall prevalence of dyslipidemia was 43.5%, and abnormal HDL, LDL, TC, and TG were 17.9%, 21.8%, 36.2%, and 44%, respectively. The multiple logistic regression showed that male (OR=1.92, 95%CI: 1.74 − 2.14), obese participants (OR༝3.0, 95%CI: 2.02–4.45), low physical activity (OR༝0.80, 95%CI: 0.76–0.97), smokers (OR༝1.17, 95%CI: 1.05 − 1.31), rich people (OR༝1.19, 95%CI: 1.04–1.36), and diabetic patients (OR༝1.63, 95%CI: 1.47 − 1.80) had a higher odds of dyslipidemia (all P-values were < 0.05). Conclusion Our findings suggest that dyslipidemia is a complex condition that is influenced by various biological and lifestyle factors. Different prevention and treatment strategies may be needed for different population subgroups.