Abstract
Purpose: To investigate the relationship between preoperative inflammatory parameters and disease severity in patients operated for perianal fistula in our clinic between 2013-2021.
Methods: Patients between the ages of 16-78 who were operated on with the diagnosis of perianal fistula in Kayseri Şehir Training and Research Hospital between 2013-2021 and who were followed up afterward were included in the study by retrospective file search method without gender discrimination. Preoperative demographic data, laboratory parameters (platelet, neutrophil, lymphocyte, monocyte, leukocyte, CRP, albumin), surgical procedures, perioperative and postoperative complications, length of stay, and recurrences were noted.
Results: 134 patients with perianal fistula were included in the study. It was determined that 71.6% (n=96) were male, and the mean age was 44.6±13.8 years. Inflammatory parameters such as crp/albumin, neutrophil/lymphocyte, lymphocyte/crp, neutrophil/crp, lymphocyte/monocyte, platelet/lymphocyte were compared with tract length, tract thickness, presence of perifistular inflammation and presence of abscess as criteria for complex fistula formation and cut of values were created. Among these scoring values, crp/albumin, lymphocyte/crp, and neutrophil/crp ratios were statistically significant in predicting the tract characteristics defined for high recurrence and complex fistula.
Conclusion: Inflammation-based scores such as crp/albumin, lymphocyte/crp, and neutrophil/crp ratios can differentiate complex fistula from simple fistula.