Validation of Serbian version of chronic obstructive pulmonary disease assessment test

Author:

Milenkovic Branislava1,Dimic-Janjic Sanja2,Kotur-Stevuljevic Jelena3,Kopitovic Ivan4,Jankovic Jelena2,Stjepanovic Mihailo1,Vukoja Marija4ORCID,Ristic Snezana5,Davicevic-Elez Zaklina6

Affiliation:

1. Clinical Center of Serbia, Clinic for Pulmonology, Belgrade, Serbia + University of Belgrade, Faculty of Medicine, Belgrade, Serbia

2. Clinical Center of Serbia, Clinic for Pulmonology, Belgrade, Serbia

3. University of Belgrade, Faculty of Pharmacy, Department for Molecular Biochemistry, Belgrade, Serbia

4. University of Novi Sad, Faculty of Medicine, Novi Sad, Serbia + Institute for Pulmonary Diseases of Vojvodina, Sremska Kamenica, Serbia

5. Institute for Students Health Care, Belgrade, Serbia

6. GlaxoSmithKline, Medical Department, Belgrade, Serbia

Abstract

Background/Aim. The Chronic obstructive pulmonary disease (COPD) Assessment Test (CAT) is a simple and reliable tool designed to measure overall COPD related health status and complement physician assessment in routine clinical practice. Objective of this study was to evaluate the validity of the Serbian version of CAT. Methods. Study included 140 outpatients in the stable COPD, recruited from two centres: Clinic for Pulmonology, Clinical Center of Serbia, Belgrade, and Institute for Pulmonary Diseases of Vojvodina, Sremska Kamenica. All patients completed pulmonary function testing ? spirometry, the CAT and the modified Medical Research Council (mMRC) dyspnea scale at baseline visit. The CAT test-retest reliability was tested in 20 patients by the same investigator (physician). Results. We demonstrated that Serbian version of CAT had high internal consistency with Cronbach?s alpha 0.88. Test-retest analysis showed good correlation between CAT scores in two time points (Spearman?s ? = 0.681, p < 0.01). In our study the CAT correlated moderately to mMRC scale (? = +0.57), weakly to FEV1 (? -0.214), was positively related to number of exacerbations, but did not showed exact regularity with change in the Global Initiative for Chronic Obstructive lung disease (GOLD) stage. Conclusion. The Serbian version of CAT is a reliable, simple and easy-to-use tool that can be used in everyday clinical practice to assess the health status of COPD patients in Serbia.

Publisher

National Library of Serbia

Subject

Pharmacology (medical),General Medicine

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