Adherence, Disease Control, and Misconceptions Related to the Use of Inhalation Therapy in Patients with Obstructive Pulmonary Diseases: A Cross-Sectional Study

Author:

Živanović Dejan12ORCID,Javorac Jovan34ORCID,Savić Dejana1,Mikić Andrijana2ORCID,Jevtić Marija567ORCID,Ilić Miroslav34ORCID,Kolarov Violeta34,Minaković Ivana89ORCID,Kolarš Bela89ORCID,Smuđa Mirjana110,Mijatović Jovin Vesna11ORCID

Affiliation:

1. Faculty of Medicine, University of Novi Sad, 21000 Novi Sad, Serbia

2. Department of Psychology, College of Human Development, 11000 Belgrade, Serbia

3. Department of Internal Medicine, Faculty of Medicine, University of Novi Sad, 21000 Novi Sad, Serbia

4. Institute for Pulmonary Diseases of Vojvodina, 21204 Sremska Kamenica, Serbia

5. Department of Hygiene, Faculty of Medicine, University of Novi Sad, 21000 Novi Sad, Serbia

6. Institute of Public Health of Vojvodina, 21000 Novi Sad, Serbia

7. Research Center on Environmental and Occupational Health, School of Public Health, Université Libre de Bruxelles (ULB), 1050 Brussels, Belgium

8. Department of General Medicine and Geriatrics, Faculty of Medicine, University of Novi Sad, 21000 Novi Sad, Serbia

9. Health Center “Novi Sad”, 21000 Novi Sad, Serbia

10. Department of Higher Medical School, Academy of Applied Studies Belgrade, 11000 Belgrade, Serbia

11. Department of Pharmacology, Toxicology and Clinical Pharmacology, Faculty of Medicine, University of Novi Sad, 21000 Novi Sad, Serbia

Abstract

Background and Objectives: Inadequate treatment of asthma and chronic obstructive pulmonary disease (COPD) might have a negative impact on their progression. Inhalation therapy is the cornerstone of pharmacotherapy for these conditions. However, challenges such as low adherence, negative attitudes, and misconceptions about inhaled medications still persist, impeding effective disease management. This study aimed to evaluate adherence, ascertain the level of disease control in asthma and COPD, explore potential misconceptions surrounding inhalation therapy among patients with obstructive lung diseases and the general population in Vojvodina, and evaluate the reliability of newly developed questionnaires employed in the study. Materials and Methods: This cross-sectional study utilized a battery of questionnaires encompassing sociodemographic data, the Asthma Control Test (ACT), the COPD Assessment Test (CAT), along with two novel questionnaires—one for assessing adherence and another for analyzing attitudes toward inhalation therapy. Statistical analyses were conducted using SPSS software, version 25.0. Results: The average ACT score among patients with asthma was 17.31, while it was 19.09 for the CAT questionnaire among COPD patients. The composite score on the newly developed adherence assessment questionnaire was 2.27, exhibiting a reliability coefficient lower than recommended (α = 0.468). Significant statistical differences emerged among sample subgroups regarding attitudes and misconceptions toward inhalation therapy. The reliability coefficient for this questionnaire was deemed satisfactory (α = 0.767). Conclusions: Adherence rates were notably suboptimal in both subgroups of the studied population. The disease control levels were higher among asthma patients, while they exhibited less prevalent misconceptions regarding inhalation therapy compared to COPD patients and the healthy population.

Publisher

MDPI AG

Reference40 articles.

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