Needle detection and localisation for robot‐assisted subretinal injection using deep learning

Author:

Zhou Mingchuan12ORCID,Guo Xiangyu1ORCID,Grimm Matthias2,Lochner Elias2,Jiang Zhongliang2,Eslami Abouzar3,Ye Juan4,Navab Nassir2,Knoll Alois2,Nasseri Mohammad Ali5

Affiliation:

1. Robotic Micro‐nano Manipulation Lab College of Biosystems Engineering and Food Science Zhejiang University Hangzhou China

2. School of Computation, Information and Technology Technische Universität München München Germany

3. Carl Zeiss Meditec AG München Germany

4. Department of Ophthalmology Second Affiliated Hospital of Zhejiang University College of Medicine Hangzhou China

5. Augenklinik und Poliklinik Klinikum rechts der Isar der Technische Universität München München Germany

Abstract

AbstractSubretinal injection is a complicated task for retinal surgeons to operate manually. In this paper we demonstrate a robust framework for needle detection and localisation in robot‐assisted subretinal injection using microscope‐integrated Optical Coherence Tomography with deep learning. Five convolutional neural networks with different architectures were evaluated. The main differences between the architectures are the amount of information they receive at the input layer. When evaluated on ex‐vivo pig eyes, the top performing network successfully detected all needles in the dataset and localised them with an Intersection over Union value of 0.55. The algorithm was evaluated by comparing the depth of the top and bottom edge of the predicted bounding box to the ground truth. This analysis showed that the top edge can be used to predict the depth of the needle with a maximum error of 8.5 μm.

Publisher

Institution of Engineering and Technology (IET)

Subject

Artificial Intelligence,Computer Networks and Communications,Computer Vision and Pattern Recognition,Human-Computer Interaction,Information Systems

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