Haematological and serum biochemical values in spontaneously epileptic male rats and related rat strains-Reference-Cited by-同舟云学术

Haematological and serum biochemical values in spontaneously epileptic male rats and related rat strains

Published:1998-04-01 Issue:2 Volume:32 Page:214-218
ISSN:0023-6772
Container-title:Laboratory Animals
language:en
Short-container-title:Lab Anim

Author:

Asano Yuzo¹,Susami Masayuki¹,Honda Katuya¹,Serikawa Tadao²

Affiliation:

1. Safety Research Laboratory, Tanabe Seiyaku Co., Ltd., Kashima 3-16-89, Yodogawa-ku, Osaka 532, Japan

2. Institute of Laboratory Animals, Faculty of Medicine, Kyoto University, Sakyo-ku, Kyoto 606-01, Japan

Abstract

Haematological and serum biochemical measurements in male spontaneously epileptic rats (SER; double mutants homozygous for zitter and tremor genes) were compared with the values for related rat strains. Some haematological values were low in TRM rats and total leukocyte counts were high in ZI and TRM rats. TRM rats showed higher total cholesterol, phospholipid, high-density lipoprotein cholesterol and calcium values, and lower albumin value than Kyo: Wistar rats. Zitter homozygous rats including SER exhibited low total cholesterol, phospholipid and high-density lipoprotein cholesterol values. The SER showed an increase in urea nitrogen, aspartate aminotransferase and alanine aminotransferase values, and a decrease in glucose value, suggesting deterioration of the whole body with age.

Publisher

SAGE Publications

Subject

General Veterinary,Animal Science and Zoology

Link

http://journals.sagepub.com/doi/pdf/10.1258/002367798780600052

Cited by 7 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Acute toxicity analysis of an inhibitor of BCL2, Disarib, in rats;Scientific Reports;2021-05-11

2. Iron accumulation in the choroid plexus, ependymal cells and CNS parenchyma in a rat strain with low‐grade haemolysis of fragile macrocytic red blood cells;Brain Pathology;2021-01-29

3. Evaluation of Maternal Reproductive Outcomes and Biochemical Analysis from Wistar Audiogenic Rats (WAR) and Repercussions in Their Offspring;Reproductive Sciences;2020-07-06

4. Performance evaluation of a formulated infant food on some biological indices in Wistar rats;Ovidius University Annals of Chemistry;2019-07-01

5. Antihypertensive and antioxidant effects of protocatechuic acid in deoxycorticosterone acetate-salt hypertensive rats;Biomedicine & Pharmacotherapy;2018-04