Maintenance and breeding of transgenic mouse strains at the scientific center of biomedical technologies of the FMBA of Russia

Author:

Petrova N. V.1,Skripkina M. M.1

Affiliation:

1. Scientific Center of Biomedical Technologies of the Federal Medical and Biological Agency of Russia

Abstract

In this article, we analyze the specifics of health monitoring and maintenance of transgenic mouse strains. A method for keeping animals in laboratory conditions is discussed, the criteria for inbred crossing of homozygous transgenic mice lines are characterized. The obtained data can be useful for the staff of vivaria in maintaining the transgenic line of mice. 

Publisher

Scientific Center for Biomedical Technologies of the Federal Medical-Biological Agency

Subject

General Medicine

Reference6 articles.

1. Averina O.A., Sergiev P.V. Vidy koloniy laboratornykh gryzunov v issledovaniyakh in vivo [Species of laboratory rodent colonies in vivo studies]. Institute of Functional Genomics of the Moscow State University, 2020. (In Russian).

2. GOST 33216-2014. Mezhgosudarstvennyy standart. Rukovodstvo po soderzhaniyu i ukhodu za laboratornymi zhivotnymi. Pravila soderzhaniya i ukhoda za laboratornymi gryzunami i krolikami [GOST 33216-2014. Interstate standard. Guidelines for the maintenance and care of laboratory animals. Rules for the maintenance and care of laboratory rodents and rabbits]. (In Russian).

3. Petrova E.S., Gromova A.V., Anisimenko M.S., Ruban L.A., Egorova S.A., Petrovskaya I.F., Amstislavskaya T.G., Lipina T.V. Podderzhanie geneticheski modifitsirovannykh liniy myshey: vklad v razvitie biokollektsiy v Rossii [Maintenance of genetically modified mouse strains: Contribution to the development of biocollections in Russia]. Laboratornye zhivotnye dlya nauchnykh issledovaniy [Laboratory animals forscientific research]. 2018;2:2–15. (In Russian). DOI: 10.29926/2618723X-2018-02-01.

4. https://www.bbt-lab.com/

5. https://meduniver.com/Medical/cardiologia/1365.html

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