In vivo live imaging of postnatal neural stem cells-Reference-Cited by-同舟云学术

In vivo live imaging of postnatal neural stem cells

Published:2021-08-12 Issue:18 Volume:148 Page:
ISSN:0950-1991
Container-title:Development
language:en
Short-container-title:

Author:

Marymonchyk Alina¹²,Malvaut Sarah¹²,Saghatelyan Armen¹²^ORCID

Affiliation:

1. CERVO Brain Research Center, Quebec City, QC, CanadaG1J 2G3

2. Department of Psychiatry and Neuroscience, Université Laval, Quebec City, QC, CanadaG1V 0A6

Abstract

ABSTRACT Neural stem cells (NSCs) are maintained in specific regions of the postnatal brain and contribute to its structural and functional plasticity. However, the long-term renewal potential of NSCs and their mode of division remain elusive. The use of advanced in vivo live imaging approaches may expand our knowledge of NSC physiology and provide new information for cell replacement therapies. In this Review, we discuss the in vivo imaging methods used to study NSC dynamics and recent live-imaging results with respect to specific intracellular pathways that allow NSCs to integrate and decode different micro-environmental signals. Lastly, we discuss future directions that may provide answers to unresolved questions regarding NSC physiology.

Funder

Canadian Institute of Health Research

Publisher

The Company of Biologists

Subject

Developmental Biology,Molecular Biology

Link

http://journals.biologists.com/dev/article-pdf/doi/10.1242/dev.199778/2100595/dev199778.pdf

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