Affiliation:
1. Chitkara University, India
2. Delhi Pharmaceutical Sciences and Research University (DPSRU), India
Abstract
Antimicrobial resistance remains a substantial global health concern, invigorating the critical need for alternate therapeutic options to combat chronic intracellular infections and biofilms so as to shorten the hospital stays, and hence mortality. Nanomaterials have been developed as delivery carriers for antibiotics to improve their penetration through these biofilms. Nanoformulations of existing antibiotics has led to enhanced bioavailability and site specificity. Moreover, diagnosis of infections using efficient nanosensors or probes may speed up the treatment process at earlier stages of infection.
Reference143 articles.
1. Different cellulosic polymers for synthesizing silver nanoparticles with antioxidant and antibacterial activities
2. Control of biofilm formation: Antibiotics and beyond.;A.Algburi;Applied and Environmental Microbiology,2016
3. Antibacterial Effect of Chitosan Nanoparticle Loaded with Nisin for the Prolonged Effect
4. Antibacterial activity of sunflower oil microemulsion.;C. H.Anjali;International Journal of Pharmacy and Pharmaceutical Sciences,2010
5. Anacardic acid encapsulated solid lipid nanoparticles for Staphylococcus aureus biofilm therapy: Chitosan and DNase coating improves antimicrobial activity.;M. M.Anjum;Drug Delivery and Translational Research,2020