The objective of this work is to predict the employment rate of students based on the information in the SSM (student status management) in colleges and universities. Firstly, the relevant content of SSM is introduced. Secondly, the BP (Back Propagation) neural network, the LM (Levenberg Marquardt) algorithm, and the BR (Bayesian Regularization) algorithm are introduced. In addition, the LM algorithm is combined with the BR algorithm to optimize the BP neural network, so as to establish a prediction model of the employment rate of college graduates based on the LM-BP neural network (the established prediction model). Finally, the established prediction model is verified after the historical data of college students in the SSM are managed and processed using the big data analysis technology. It suggests that the established prediction model shows higher prediction accuracy, more stable prediction performance, more ideal prediction effect, and higher practical application value.