Affiliation:
1. Siddaganga Institute of Technology, India
2. GenEclat Technologies, India
Abstract
In this chapter, the complete overview and application of Big Data analysis in the field of health care industries, Clinical Informatics, Personalized Medicine and Bioinformatics is provided. The major tools and databases used for the Big Data analysis are discussed in this chapter. The development of sequencing machines has led to the fast and effective ways of generating DNA, RNA, Whole Genome data, Transcriptomics data, etc. available in our hands in just a matter of hours. The complete Next Generation Sequencing (NGS) huge data analysis work flow for the medicinal plants are discussed in the chapter. This chapter serves as an introduction to the big data analysis in Next Generation Sequencing and concludes with a summary of the topics of the remaining chapters of this book.
Reference92 articles.
1. A map of human genome variation from population-scale sequencing
2. A review of data mining using big data in health informatics.;O.Access;Journal of Big Data,2014
3. Basic local alignment search tool
4. Andrews, S. (2016). A quality control tool for high throughput sequence data. Retrieved on June 29, 2016 from https://www.bioinformatics.babraham.ac.uk/projects/fastqc/
5. Trimmomatic: a flexible trimmer for Illumina sequence data