Physiologically Based Pharmacokinetic Modeling to Investigate Regional Brain Distribution Kinetics in Rats-Reference-Cited by-同舟云学术

Physiologically Based Pharmacokinetic Modeling to Investigate Regional Brain Distribution Kinetics in Rats

Published:2012-05-17 Issue:3 Volume:14 Page:543-553
ISSN:1550-7416
Container-title:The AAPS Journal
language:en
Short-container-title:AAPS J

Author:

Westerhout Joost,Ploeger Bart,Smeets Jean,Danhof Meindert,de Lange Elizabeth C. M.

Publisher

Springer Science and Business Media LLC

Subject

Pharmaceutical Science

Link

http://link.springer.com/content/pdf/10.1208/s12248-012-9366-1.pdf

Reference52 articles.

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3. Westerhout J, Danhof M, de Lange ECM. Preclinical prediction of human brain target site concentrations: considerations in extrapolating to the clinical setting. J Pharm Sci. 2011;100:3577–93.

4. Feng MR. Assessment of blood–brain barrier penetration: in silico, in vitro and in vivo. Curr Drug Metab. 2002;3:647–57.

5. Bickel U. How to measure drug transport across the blood–brain barrier. NeuroRx. 2005;2:15–26.

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