Preclinical Prediction of Human Brain Target Site Concentrations: Considerations in Extrapolating to the Clinical Setting

Author:

Westerhout Joost,Danhof Meindert,De Lange Elizabeth C.M.

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference159 articles.

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5. Active-site concentrations of chemicals—Are they a better predictor of effect than plasma/organ/tissue concentrations;Hammarlund-Udenaes;Basic Clin Pharmacol Toxicol,2009

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