A Novel Total Drug Assay for Quantification of Anti-C5 Therapeutic Monoclonal Antibody in the Presence of Abundant Target-Reference-Cited by-同舟云学术

A Novel Total Drug Assay for Quantification of Anti-C5 Therapeutic Monoclonal Antibody in the Presence of Abundant Target

Published:2021-01 Issue:1 Volume:23 Page:
ISSN:1550-7416
Container-title:The AAPS Journal
language:en
Short-container-title:AAPS J

Author:

Watanabe Hiroo,Shibuya Mitsuko,Shibahara Norihito,Ruike Yoshinao,Sampei Zenjiro,Haraya Kenta,Tachibana Tatsuhiko,Wakabayashi Tetsuya,Sakamoto Akihisa,Tsunoda Hiroyuki,Murao Naoaki

Publisher

Springer Science and Business Media LLC

Subject

Pharmaceutical Science

Link

http://link.springer.com/content/pdf/10.1208/s12248-020-00539-9.pdf

Reference37 articles.

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2. Lee JW, Kelley M, King LE, Yang J, Salimi-Moosavi H, Tang MT, et al. Bioanalytical approaches to quantify “total” and “free” therapeutic antibodies and their targets: technical challenges and PK/PD applications over the course of drug development. AAPS J. 2011;13(1):99–110.

3. Mayer AP, Hottenstein CS. Ligand-binding assay development: what do you want to measure versus what you are measuring? AAPS J. 2016;18(2):287–9.

4. Heinrich J, Staack RF, Stubenrauch KG, Papadimitriou A. Proposal for a harmonized descriptive analyte nomenclature for quantitative large-molecule bioanalysis. Bioanalysis. 2015;7(24):3057–62.

5. Shih JY, Patel V, Watson A, Hager T, Luan P, Salimi-Moosavi H, et al. Implementation of a universal analytical method in early-stage development of human antibody therapeutics: application to pharmacokinetic assessment for candidate selection. Bioanalysis. 2012;4(19):2357–65.

Cited by 3 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Overcoming Soluble Target Interference in Measurement of Total Bispecific Therapeutic Antibody Concentrations;The AAPS Journal;2023-08-18

2. Assay pH and critical reagent optimization in measuring concentrations of a monoclonal antibody and its target;Bioanalysis;2022-04

3. Correction to: A Novel Total Drug Assay for Quantification of Anti-C5 Therapeutic Monoclonal Antibody in the Presence of Abundant Target;The AAPS Journal;2021-01-20