Spatial Network Mapping of Pulmonary Multidrug-Resistant Tuberculosis Cavities Using RNA Sequencing

Author:

Dheda Keertan12,Lenders Laura1,Srivastava Shashikant34,Magombedze Gesham3,Wainwright Helen5,Raj Prithvi4,Bush Stephen J.3,Pollara Gabriele6ORCID,Steyn Rachelle7,Davids Malika1,Pooran Anil1,Pennel Timothy8,Linegar Anthony8,McNerney Ruth1,Moodley Loven8,Pasipanodya Jotam G.3,Turner Carolin T.6,Noursadeghi Mahdad6ORCID,Warren Robin M.9,Wakeland Edward4,Gumbo Tawanda13ORCID

Affiliation:

1. Centre for Lung Infection and Immunity, Division of Pulmonology, Department of Medicine and UCT Lung Institute and South African MRC/UCT Centre for the Study of Antimicrobial Resistance, University of Cape Town, Cape Town, South Africa

2. Faculty of Infectious and Tropical Diseases, Department of Immunology and Infection, London School of Hygiene and Tropical Medicine, London, United Kingdom

3. Center for Infectious Diseases Research and Experimental Therapeutics, Baylor Research Institute, Baylor University Medical Center, Dallas, Texas

4. Department of Immunology, University of Texas Southwestern Medical Center, Dallas, Texas

5. Department of Pathology

6. Division of Infection and Immunity, University College London, London, United Kingdom; and

7. Department of Nuclear Medicine, and

8. Chris Barnard Division of Cardiothoracic Surgery, Department of Surgery, Groote Schuur Hospital, University of Cape Town, Cape Town, South Africa

9. South African Medical Research Council Centre for Tuberculosis Research/Department of Science and Technology/National Research Foundation Centre of Excellence for Biomedical Tuberculosis Research, Division of Molecular Biology and Human Genetics, Stellenbosch University, Cape Town, South Africa

Publisher

American Thoracic Society

Subject

Critical Care and Intensive Care Medicine,Pulmonary and Respiratory Medicine

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