Improving Our Aim: Targeting Therapy with Roflumilast in Patients with Severe and Very Severe Chronic Obstructive Pulmonary Disease
Author:
Affiliation:
1. Division of Pulmonary and Critical Care MedicineBrigham and Women’s Hospital and Harvard Medical SchoolBoston, Massachusettsand
2. The Lovelace Respiratory Research InstituteAlbuquerque, New Mexico
Publisher
American Thoracic Society
Subject
Critical Care and Intensive Care Medicine,Pulmonary and Respiratory Medicine
Link
https://www.atsjournals.org/doi/pdf/10.1164/rccm.201806-1051ED
Reference5 articles.
1. Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease 2017 Report. GOLD Executive Summary
2. Determinants of Response to Roflumilast in Severe Chronic Obstructive Pulmonary Disease. Pooled Analysis of Two Randomized Trials
3. Effect of roflumilast on exacerbations in patients with severe chronic obstructive pulmonary disease uncontrolled by combination therapy (REACT): a multicentre randomised controlled trial
4. Effect of Roflumilast and Inhaled Corticosteroid/Long-Acting β2-Agonist on Chronic Obstructive Pulmonary Disease Exacerbations (RE2SPOND). A Randomized Clinical Trial
5. Mepolizumab for Eosinophilic Chronic Obstructive Pulmonary Disease
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1. Discovery of (S)-2-(1-(4-Amino-3-(3-fluoro-4-methoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)propyl)-3-cyclopropyl-5-fluoroquinazolin-4(3H)-one (IHMT-PI3Kδ-372) as a Potent and Selective PI3Kδ Inhibitor for the Treatment of Chronic Obstructive Pulmonary Disease;Journal of Medicinal Chemistry;2020-11-12
2. Update in Chronic Obstructive Pulmonary Disease 2018;American Journal of Respiratory and Critical Care Medicine;2019-06-15
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