Might Brushed Nasal Cells Be a Surrogate for CFTR Modulator Clinical Response?-Reference-Cited by-同舟云学术

Might Brushed Nasal Cells Be a Surrogate for CFTR Modulator Clinical Response?

Published:2019-01 Issue:1 Volume:199 Page:123-126
ISSN:1073-449X
Container-title:American Journal of Respiratory and Critical Care Medicine
language:en
Short-container-title:Am J Respir Crit Care Med

Author:

Pranke Iwona¹,Hatton Aurelie¹,Masson Alexandra²³,Flament Thomas⁴,Le Bourgeois Muriel²,Chedevergne Frederique²,Bailly Celine²,Urbach Valerie¹,Hinzpeter Alexandre¹,Edelman Aleksander¹,Sermet-Gaudelus Isabelle¹²⁵

Affiliation:

1. Institut Necker-Enfants MaladesParis, France

2. Hôpital Necker-Enfants MaladesParis, France

3. Hôpital DupuytrenLimoges, France

4. Hôpital BretonneauTours, Franceand

5. Université Paris SorbonneParis, France

Publisher

American Thoracic Society

Subject

Critical Care and Intensive Care Medicine,Pulmonary and Respiratory Medicine

Link

https://www.atsjournals.org/doi/pdf/10.1164/rccm.201808-1436LE

Reference6 articles.

1. Cystic fibrosis

2. Sweat chloride as a biomarker of CFTR activity: Proof of concept and ivacaftor clinical trial data

3. Lumacaftor–Ivacaftor in Patients with Cystic Fibrosis Homozygous for Phe508del CFTR

4. Pranke I, Veit G, Golec A, Hatton AN, Guyen T, Kyrilli S, et al. May the primary human nasal epithelial cell cultures be considered as a biomarker to predict the clinical efficacy of CFTR modulators? Presented at the 15th European Cystic Fibrosis Society Basic Science Conference. March 21–24, 2018, Loutraki, Greece. Abstract 127.

5. Correction of CFTR function in nasal epithelial cells from cystic fibrosis patients predicts improvement of respiratory function by CFTR modulators

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