Bone Morphogenetic Protein 9 Is a Mechanistic Biomarker of Portopulmonary Hypertension

Author:

Nikolic Ivana1ORCID,Yung Lai-Ming1ORCID,Yang Peiran1ORCID,Malhotra Rajeev2ORCID,Paskin-Flerlage Samuel D.1,Dinter Teresa1ORCID,Bocobo Geoffrey A.1,Tumelty Kathleen E.3,Faugno Anthony J.4,Troncone Luca1,McNeil Megan E.1,Huang Xiuli5,Coser Kathryn R.3,Lai Carol S. C.1,Upton Paul D.6ORCID,Goumans Marie Jose7ORCID,Zamanian Roham T.8ORCID,Elliott C. Gregory9,Lee Arthur5,Zheng Wei5,Berasi Stephen P.3,Huard Christine3,Morrell Nicholas W.6ORCID,Chung Raymond T.10,Channick Richard W.11,Roberts Kari E.4,Yu Paul B.1ORCID

Affiliation:

1. Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts

2. Division of Cardiology

3. Pfizer Centers for Therapeutic Innovation, Cambridge, Massachusetts

4. Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, Tufts Medical Center, Boston, Massachusetts

5. Therapy for Rare and Neglected Diseases Program, National Center for Advancing Translational Sciences, Rockville, Maryland

6. Division of Respiratory Medicine, Department of Medicine, University of Cambridge School of Clinical Medicine, Addenbrooke’s and Papworth Hospitals, Cambridge, United Kingdom

7. Department of Molecular Cell Biology and Cancer Genomics Centre Netherlands, Leiden University Medical Centre, Leiden, the Netherlands

8. Division of Pulmonary and Critical Care Medicine, Department of Medicine, Stanford University Medical Center, Stanford, California; and

9. Department of Medicine, Intermountain Medical Center and University of Utah, Salt Lake City, Utah

10. Gastrointestinal Unit and Liver Center, and

11. Division of Pulmonary and Critical Care Medicine, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts

Publisher

American Thoracic Society

Subject

Critical Care and Intensive Care Medicine,Pulmonary and Respiratory Medicine

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