Unveiling the Impact of BMP9 in Liver Diseases: Insights into Pathogenesis and Therapeutic Potential-Reference-Cited by-同舟云学术

Unveiling the Impact of BMP9 in Liver Diseases: Insights into Pathogenesis and Therapeutic Potential

Published:2024-08-15 Issue:8 Volume:14 Page:1013
ISSN:2218-273X
Container-title:Biomolecules
language:en
Short-container-title:Biomolecules

Author:

Chen Han¹²,Li Ying-Yi³^ORCID,Nio Kouki³^ORCID,Tang Hong¹²

Affiliation:

1. Center of Infectious Diseases, West China Hospital of Sichuan University, Chengdu 610041, China

2. Laboratory of Infectious and Liver Diseases, Institute of Infectious Diseases, West China Hospital of Sichuan University, Chengdu 610041, China

3. Department of Gastroenterology, Kanazawa University Hospital, Kanazawa 9208641, Japan

Abstract

Bone morphogenetic proteins (BMPs) are a group of growth factors belonging to the transforming growth factor β(TGF-β) family. While initially recognized for their role in bone formation, BMPs have emerged as significant players in liver diseases. Among BMPs with various physiological activities, this comprehensive review aims to delve into the involvement of BMP9 specifically in liver diseases and provide insights into the complex BMP signaling pathway. Through an enhanced understanding of BMP9, we anticipate the discovery of new therapeutic options and potential strategies for managing liver diseases.

Funder

National Key Research and Development Program of China

1.3.5 project for disciplines of excellence, West China Hospital, Sichuan University

Publisher

MDPI AG

Link

https://www.mdpi.com/2218-273X/14/8/1013/pdf

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