Long Noncoding RNA TYKRIL Plays a Role in Pulmonary Hypertension via the p53-mediated Regulation of PDGFRβ

Author:

Zehendner Christoph M.123,Valasarajan Chanil4,Werner Astrid12,Boeckel Jes-Niels13,Bischoff Florian C.123,John David13,Weirick Tyler135,Glaser Simone F.13,Rossbach Oliver6,Jaé Nicolas1,Demolli Shemsi1,Khassafi Fatemeh4,Yuan Ke7,de Jesus Perez Vinicio A.7,Michalik Katharina M.1,Chen Wei89,Seeger Werner410,Guenther Andreas10,Wasnick Roxana M.10,Uchida Shizuka15,Zeiher Andreas M.23,Dimmeler Stefanie13,Pullamsetti Soni S.410ORCID

Affiliation:

1. Institute for Cardiovascular Regeneration, Centre for Molecular Medicine, and

2. ZIM III, Department of Cardiology, Goethe University, Frankfurt am Main, Germany

3. German Center for Cardiovascular Research, DZHK, Berlin, Germany

4. Department of Lung Development and Remodeling, Max Planck Institute for Heart and Lung Research, member of the German Center for Lung Research (DZL), Bad Nauheim, Germany

5. Cardiovascular Innovation Institute, University of Louisville, Louisville, Kentucky

6. Department of Biology and Chemistry, Institute of Biochemistry, University of Giessen, Giessen, Germany

7. Division of Pulmonary and Critical Care Medicine, Stanford University, Stanford, California

8. Laboratory for Novel Sequencing Technology, Functional and Medical Genomics, Berlin Institute for Medical Systems Biology, Max-Delbruck-Centre for Molecular Medicine, Berlin, Germany

9. Department of Biology, Southern University of Science and Technology, Shenzhen, Guangdong, China; and

10. Department of Internal Medicine, Universities of Giessen and Marburg Lung Center (UGMLC), member of the DZL, Justus Liebig University, Giessen, Germany

Publisher

American Thoracic Society

Subject

Critical Care and Intensive Care Medicine,Pulmonary and Respiratory Medicine

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