Trikafta Rescues CFTR and Lowers Monocyte P2X7R-induced Inflammasome Activation in Cystic Fibrosis-Reference-Cited by-同舟云学术

Trikafta Rescues CFTR and Lowers Monocyte P2X7R-induced Inflammasome Activation in Cystic Fibrosis

Published:2022-04-01 Issue:7 Volume:205 Page:783-794
ISSN:1073-449X
Container-title:American Journal of Respiratory and Critical Care Medicine
language:en
Short-container-title:Am J Respir Crit Care Med

Author:

Gabillard-Lefort Claudie¹^ORCID,Casey Michelle¹²^ORCID,Glasgow Arlene M. A.³^ORCID,Boland Fiona⁴^ORCID,Kerr Orla²,Marron Elaine²,Lyons Anne-Marie²,Gunaratnam Cedric¹²,McElvaney Noel G.¹²,Reeves Emer P.¹^ORCID

Affiliation:

1. The Irish Centre of Genetic Lung Disease, Department of Medicine,

2. Cystic Fibrosis Unit, Department of Respiratory Medicine, Beaumont Hospital, Dublin, Ireland

3. Department of Clinical Microbiology, and

4. Data Science Centre, Royal College of Surgeons in Ireland, Dublin, Ireland; and

Funder

Cystic Fibrosis Foundation

Publisher

American Thoracic Society

Subject

Critical Care and Intensive Care Medicine,Pulmonary and Respiratory Medicine

Link

https://www.atsjournals.org/doi/pdf/10.1164/rccm.202106-1426OC

Reference50 articles.

1. Identification of the Cystic Fibrosis Gene: Cloning and Characterization of Complementary DNA

2. Cystic fibrosis

3. CFTR Modulators: The Changing Face of Cystic Fibrosis in the Era of Precision Medicine

4. A Phase 3 Open-Label Study of Elexacaftor/Tezacaftor/Ivacaftor in Children 6 through 11 Years of Age with Cystic Fibrosis and at Least One F508del Allele

5. Efficacy and safety of the elexacaftor plus tezacaftor plus ivacaftor combination regimen in people with cystic fibrosis homozygous for the F508del mutation: a double-blind, randomised, phase 3 trial

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