A Phase 3 Open-Label Study of Elexacaftor/Tezacaftor/Ivacaftor in Children 6 through 11 Years of Age with Cystic Fibrosis and at Least One F508del Allele

Author:

Zemanick Edith T.1,Taylor-Cousar Jennifer L.23,Davies Jane4,Gibson Ronald L.5,Mall Marcus A.678ORCID,McKone Edward F.9,McNally Paul10ORCID,Ramsey Bonnie W.5,Rayment Jonathan H.11,Rowe Steven M.12ORCID,Tullis Elizabeth13,Ahluwalia Neil14,Chu Chenghao14,Ho Thang14,Moskowitz Samuel M.14,Noel Sabrina14,Tian Simon14,Waltz David14,Weinstock Tanya G.14,Xuan Fengjuan14,Wainwright Claire E.15,McColley Susanna A.1617

Affiliation:

1. Department of Pediatrics, University of Colorado Anschutz Medical Campus and Children’s Hospital Colorado, Aurora, Colorado;

2. Department of Medicine and

3. Department of Pediatrics, National Jewish Health, Denver, Colorado;

4. National Heart and Lung Institute, Imperial College London, National Institute for Health Research Imperial Biomedical Research Centre and Royal Brompton and Harefield National Health Service Foundation Trust, London, United Kingdom;

5. University of Washington/Seattle Children’s Hospital, Seattle, Washington;

6. Department of Pediatric Pulmonology, Immunology and Intensive Care Medicine, Charité–Universitätsmedizin Berlin, Berlin, Germany;

7. Berlin Institute of Health, Berlin, Germany;

8. German Center for Lung Research, Berlin, Germany;

9. St. Vincent’s University Hospital and University College, Dublin, Ireland;

10. Children’s Health Ireland and Royal College of Surgeons in Ireland University of Medicine and Health Sciences, Dublin, Ireland;

11. British Columbia Children’s Hospital, Vancouver, British Columbia, Canada;

12. University of Alabama at Birmingham, Birmingham, Alabama;

13. St. Michael’s Hospital, Toronto, Ontario, Canada;

14. Vertex Pharmaceuticals Incorporated, Boston, Massachusetts;

15. University of Queensland, Brisbane, Queensland, Australia;

16. Ann and Robert H. Lurie Children’s Hospital of Chicago, Chicago, Illinois; and

17. Northwestern University Feinberg School of Medicine, Chicago, Illinois

Publisher

American Thoracic Society

Subject

Critical Care and Intensive Care Medicine,Pulmonary and Respiratory Medicine

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