Vitamin D in edible mushrooms: biosynthesis, contents, bioavailability, and nutritional significance

Abstract

Edible mushrooms exposed to sunlight or UV irradiation convert ergosterol to ergocalciferol (vitamin D₂), which is well absorbed and has a similar bioavailability to vitamin D₃. Consumption of vitamin D₂ – enhanced mushrooms significantly increases circulating levels of 25-hydroxyvitamin D₂ that is further metabolized to the biologically active form – 1,25(OH)₂D₂. Dietary supplementation with UV-irradiated mushrooms has been shown to lower parathyroid hormone (PTH) concentrations in the blood and to increase bone mineral density, to suppress an immune response, to decrease circulating plasminogen activator inhibitor 1 (PAI-1) levels, as well as to improve cognitive performance in dementia syndromes. Current evidence indicates that more than half of the world’s population is vitamin D deficient, mushrooms enriched with ergocalciferol may therefore prove useful as a natural dietary source of this vitamin – incorporating them into the diet can help meet the body’s daily requirement and restore vitamin D status.