Affiliation:
1. State Educational Organization of Higher Professional Education «M. Gorky Donetsk National Medical University»
2. State Educational Organization of Higher Professional Education «M. Gorky Donetsk National Medical University»; State Institution «Institute of Urgent and Reconstructive Surgery named after V.K. Gusak»
3. Federal State Budgetary Educational Institution of Higher Education «Saratov State Medical University named after V.I. Razumovsky»
Abstract
The review contains information about the most common pathogens of infective endocarditis (IE) in certain categories of patients. Basing on analysis of current national and foreign sources concerning IE study there are description of conditions favoring to dominance of various microorganisms in intravenous drug users, HIV-infected patients, patients on hemodialysis, with valve prostheses, diabetes mellitus and malignant neoplasm patients, elderly patients, and pregnant women.Distribution of both as typical for IE (staphylococci, streptococci, enterococci) and rare microorganisms as well polymicrobial endocarditis in mentioned above groups is considered. There is discussion about possible reasons of prevalence of methicillin-sensitive or methicillin-resistant Staphylococcus aureus species in different IE patient categories, disease development initiated by rare forms of microbial agents in immunosuppressive patients, microbial flora features depending on terms valvular infection after valve prosthetics. Despite on consideration about predominance of one or another microorganism as an etiologic agent of IE in given clinical situation, during medical help providing it should strive for precise verification of an etiologic factor for choice of effective antibacterial treatment.