Evaluation of oxygen consumption at biologically active surfaces using scanning electrochemical microscopy

Abstract

Abstract Scanning electrochemical microscopy (SECM) is a local electrochemical analysis technique, which performs scanning of the sample by ultramicroelectrode (UME) [1]. The result of measurement usually is current, which depends on the electrochemical properties of the surface of interest. The errors can be observed if UME geometry is not ideal [2,3]. This happens after UME polishing or breaking after contact with the sample surface. And the aim of this research was to evaluate oxygen consumption at biologically active surfaces using scanning electrochemical microscopy. That is why the oxygen consumption at the surface of interest with UME of different geometry was evaluated in this work. The model results were compared with experimental data. The computational experiment was performed with the SECM model using diffusion equations in the COMSOL program. This model could be further improved to measure diffusion rates with different probe geometries and coefficients.