Effects of Petroselinum crispum extract versus fat diet and Dexamethasone induced organ injuries in mice

Abstract

Abstract Petroselinum crispumis a herb belonging to the Apiaceae family,it has been usually used for the management of many inflammatory disease due to many pharmacological effects of corticosteroid with a strong anti-inflammatory and immunosuppressant properties (ex. dexamethasone), it is famous to cause side effects. It was clearly observed that dexamethasone could induced liver renal and increase the lipid profile in mice. The Petroselinum crispum methanol extract was prepared by soaking of 200 g of each of the pure dry in 1 liter of 90% methyl alcohol with shaking for 5 days, The selected animal groups (eight animals per each group) were grouped as follows Positive control group 1, negative control group 2, group 3 (10%) Petroselinum crispum treated and group 4 (20%). Petroselinum crispumtreated group it was found that Petroselinum crispumhas a clear ant atherosclerosis and a potent liver protection effects.