Abstract
Abstract
Human mobility, contact patterns, and their interplay are key aspects of our social behavior that shape the spread of infectious diseases across different regions. In the light of new evidence and data sets about these two elements, epidemic models should be refined to incorporate both the heterogeneity of human contacts and the complexity of mobility patterns. Here, we propose a theoretical framework that allows accommodating these two aspects in the form of a set of Markovian equations. We validate these equations with extensive mechanistic simulations and derive analytically the epidemic threshold. The expression of this critical value allows us to evaluate its dependence on the specific demographic distribution, the structure of mobility flows, and the heterogeneity of contact patterns, thus shedding light on the microscopic mechanisms responsible for the epidemic detriment driven by recurrent mobility patterns reported in the literature.
Funder
Secretaría de Estado de Investigación, Desarrollo e Innovación
Fundación Bancaria Ibercaja
Generalitat de Catalunya
Gobierno de Aragón
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
James S. McDonnell Foundation
Fundação de Amparo à Pesquisa do Estado de Minas Gerais
Subject
General Physics and Astronomy
Cited by
15 articles.
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