Modelling chronic hepatitis B using the Marchuk-Petrov model

Abstract

Abstract Systems of time-delay differential equations are widely used to study the dynamics of infectious diseases and immune responses. The Marchuk-Petrov model is one of them. Stable non-trivial steady states and stable periodic solutions to this model can be interpreted as chronic viral diseases. In this work we briefly describe our technology developed for computing steady and periodic solutions of time-delay systems and present and discuss the results of computing periodic solutions for the Marchuk-Petrov model with parameter values corresponding to the hepatitis B infection.