Degrons in protein substrates program the speed and operating efficiency of the AAA+ Lon proteolytic machine
Author:
Publisher
Proceedings of the National Academy of Sciences
Subject
Multidisciplinary
Reference30 articles.
1. PROTEASES AND THEIR TARGETS IN ESCHERICHIA COLI
2. ATP-dependent proteases of bacteria: recognition logic and operating principles
3. Sculpting the Proteome with AAA+ Proteases and Disassembly Machines
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2. Structural and mechanistic studies on human LONP1 redefine the hand-over-hand translocation mechanism;2024-06-25
3. Toxin-based screening of C-terminal tags inEscherichia colireveals the exceptional potency of ssrA-like degrons;2024-01-31
4. The heat shock protein LarA activates the Lon protease in response to proteotoxic stress;Nature Communications;2023-11-22
5. Lon degrades stable substrates slowly but with enhanced processivity, redefining the attributes of a successful AAA+ protease;Cell Reports;2023-09
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